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BioMers Pte Ltd

The world's only completely translucent braces system

BioMers is a Singapore-based medical technology company which has developed SimpliClear®, the world's only completely translucent braces system for orthodontic treatment. The product is set to fundamentally transform the global market for orthodontic devices. SimpliClear® is a new option for orthodontic treatment based on nanomaterials that combines clear aesthetics and excellent clinical outcomes.

BioMers was founded in 2005 as a spin-off from the renowned National University of Singapore (NUS), where the base technology was invented. The company holds an exclusive license from NUS. While headquarters, R&D and manufacturing are in Singapore, it also has a branch office in the US. BioMers is currently in the international expansion phase.

Nanostart Asia closed its initial series-A investment in BioMers in December 2009, with a follow up investment in August 2010. In October 2011, Nanostart Asia led a 6.5 million SGD series-B round, after which it owns about 22% of the company’s equity. The investment ist held via Nanostart Singapore Early Stage Venture Fund I.


The core proposition behind the SimpliClear® technology is its unique and almost invisible archwire that is made of a specifically designed composite. It is targeting the aesthetic orthodontic market segment which is recognised as a large growth market with currently only a limited number of treatment options available. Many of those are limited with respect to the patient cases that can be addressed, due to limitations in terms of clinical effectiveness. SimpliClear®, with its effectiveness in addressing a broad range of patient cases, offers a new standard of care in the aesthetic segment.


Websites: (consumers) (doctors)


The global market for orthodontic braces (arch wires and brackets) and retainers (worn by patients following treatment with braces) is currently estimated at some USD 2.4 billion annually. Over the past nine years, the U.S. market for orthodontics has grown at an annual rate of approx. 7.5 percent per year, while various regions in Asia have seen orthodontics grow at double-digit rates. The company has already received regulatory approval for its orthodontic products in the United States, the European Union and Japan. The capital invested by Nanostart is primarily used to expand sales and marketing efforts on the one hand and ramp up manufacturing on the other.

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